Unfortunately we have not noticed any improvement. She has every item in the bundle daily and I will keep trying, but for the moment sadly no better. She hates the taste of all of them to, so I have to syringe them in. She is also on daily doses of pred mix oral as otherwise she develops debilitating mouth ulcers and rips out her hair from chewing herself. I rescued her from a construction site 18 months ago and she was incredibly ill. Her allergies are the last remaining issue. She has healthy, balanced home cooked meals so it doesnt stem from that, we will persist and hopefully see improvements in time